C403.2.1 Zone Isolation Required
HVAC systems serving zones that are intended to operate or be occupied nonsimultaneously shall be divided into isolation areas. Zones may be grouped into a single isolation area provided it does not exceed 25,000 square feet (2323 m2) of conditioned floor area nor include more than one floor. Each isolation area shall be equipped with isolation devices and controls configured to automatically shut off the supply of conditioned air and outdoor air to and exhaust air from the isolation area. Each isolation area shall be controlled independently by a device meeting the requirements of Section C403.4.2.2. Central systems and plants shall be provided with controls and devices that will allow system and equipment operation for any length of time while serving only the smallest isolation area served by the system or plant.